I'm always happy to hear from undergraduates, graduates and Postdocs that are excited by the research of the group. I will be offering several projects for MEng and MSc students, so please check them out. For excellent graduate students, it is possible to apply for funding through the Department or the College , so contact me if interested. I'm also potentially able to support applications for independent Postdoctoral positions, such as Imperial's excellent Research Fellowships that I myself benefited from, or Newton Fellowships for international visiting researchers.

 

Two PDRA positions (one theory, one experimental): Genetically-encoded RNA-based circuits for synthetic biology and nanotechnological applications

We are looking for two Research Associates to work on a project developing genetically-encoded RNA-based circuits for synthetic biology and nanotechnological applications. Such circuits will combine the modularity, designability and low genetic burden of nucleic-acid systems with the flexibility of genetic circuits that can operate continuously and autonomously. The post holder will work closely with Dr Guy-Bart Stan, Dr Thomas Ouldridge and their groups, http://www.bg.ic.ac.uk/research/g.stan/group / http://www.imperial.ac.uk/principles-of-biomolecular-systems/.

PDRA 1 (experimental)

Initially, the work will focus on genetic encoding and production of individual circuit components in vitro. Subsequently, the appointee will combine these individual genetically-encoded components into functional networks and feedback control architectures in vitro in collaboration with PDRA 2. Finally, the appointee will demonstrate the operation of these motifs in E. coli.

We seek a highly motivated individual in possession of a PhD or equivalent demonstrating expertise in synthetic biology, molecular microbiology, systems biology, cellular engineering or nucleic acid nanotechnology. Postdoctoral experience in a synthetic biology or related lab would be beneficial.

The ideal candidate will have expertise in E. coli synthetic biology and/or engineering of cell-free molecular systems. He or she will be proficient in genetic engineering, including designing and cloning genes using next generation cloning methods (e.g. Gibson, Golden Gate, BASIC, etc.). Experience of standard molecular biology techniques and molecular engineering are essential. The post is funded by the Engineering and Physical Sciences Research Council (EPSRC).

For full details and the application form, please visit this page.

PDRA 2 (theory)

The appointee will explore the design principles of nucleic-acid based control architectures functioning in an environment of continuous component turnover and potential leak reactions. Subsequently, these findings will be used to develop functional RNA-based systems in vitro and in E. coli, in collaboration with PDRA 1.

We seek a highly motivated individual to fill this post, in possession of a PhD or equivalent demonstrating expertise in the analysis of deterministic and/or stochastic dynamical systems. The ideal candidate would show the ability to investigate such systems both analytically and through numerical methods and/or simulation, and would previously have developed computational tools for the use of collaborators. In addition, experience in the modelling of biomolecular systems, knowledge of the principles of feedback control, and understanding of nucleic-acid-based nanotechnology would be beneficial. The post is funded by the UK Engineering and Physical Sciences Research Council (EPSRC).

For full details and the application form, please visit this page.