Our current research portfolio is funded by the EPSRC, and the Wellcome Trust. All our projects are collaborative, multidisciplinary and endeavour to explore the limits, extend current capabilities and develop next generation neural interface technology.Conceptual image of a brain connected to a laptop

Project TitleBrief DescriptionDurationFunded by
CANDO: Controlling Abnormal Network Dynamics with Optogenetics A world-class, multi-site, cross-disciplinary project to develop a cortical implant for optogenetic neural control. Over seven years the project will progress through several phases. Initial phases focus on technology design and development, followed by rigorous testing of performance and safety. The aim is to create a first-in-human-trial in the seventh year in patients with focal epilepsy. 2014-21 Wellcome Trust/EPSRC Innovative Engineering for Health
ENGINI: Empowering Next Generation Implantable Neural Interfaces Neural interfaces will in the future need to observe the activity of many thousands of neurons. This will improve the effectiveness of neural decoding strategies by increasing the underlying information transfer rate. The availability of such a technology would be a true game changer, enabling new scientific and prosthetic applications. Our vision is that to achieve this, neural interfaces need to be distributed across multiple devices, each being autonomous and fully wireless. ENGINI is developing a new breed of mm-scale neural microsystems that directly tackle the grand challenges of long term stability, energy efficiency, and scalability. 2015-20 EPSRC Early Career Fellowship
Functional neuroimaging using ultra-wideband impulse radar We will investigate the feasibility of using microwave techniques for non-invasive functional neuroimaging. Specifically, we will use a single chip implementation of an impulse-radio ultra-wideband (IR-UWB) radar system to detect changes in regional cerebral blood volume. 2015- EPSRC DTA
Microdevices to Investigate Sleep and Temperature Regulation in Mice Sleep is essential for all animals, yet its specific function is unknown. Moreover, the overlap between the neuronal circuitry underlying sleep, the actions of sedative drugs, and temperature regulation is a mystery. Because of the power of genetics, mice are ideal animals to investigate sleep and temperature regulation, yet their small size makes recording brain waves and temperature a challenge. This project will develop two microdevices, one that will allow continuous recording of these parameters over many days, and the other will allow the brain temperature to be clamped, so that the impact of temperature can be investigated in both sleep and sedation. 2016-2019 EPSRC DTC Neurotechnology
Optical Neural Recording for Large-Scale Activity Monitoring  The aim of this project is to develop a method to detect neural activity optically without the use of any external marker, by measuring the changes in the refractive index of neurons during activity.  2015- EPSRC DTA
SenseBack: Enabling Technologies for Sensory Feedback in Next-Generation Assistive Devices The goal of this project is to develop technologies that will enable the next generation of assistive devices to provide truly natural control through enhanced sensory feedback. To enable this level of feedback, we must meet two clear objectives: to generate artificial signals that mimic those of the natural arm and hand, and to provide a means of delivering those signals to the nervous system of a prosthesis user.  2015-18 EPSRC Project & EPSRC DTC HiPEDS
 
Summary of the table's contents