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PhD example projects

These are examples of previous project titles offered to students within the CMBI. Please note that these are just for reference and the availability of projects is subject to change each year. Please do not contact the supervisor to discuss these projects specifically (as some of them will already have been allocated to students) - the links to the supervisors' webpages allow potential applicants to explore in further detail the research covered by each PI group.

Project TitlePrincipal Supervisor
Manipulating cell trafficking by bacterial effector proteins Dr Abigail Clements
The molecular basis of Agr regulation in small colony variants of Staphylococcus aureus Dr Andrew Edwards
The molecular basis of Staphylococcus aureus persistence Dr Andrew Edwards
Cell wall biogenesis of Clostridium difficile Professor Neil Fairweather
The Type Six Secretion System as a protein shuttle service to deliver effectors in target prokaryotic and eukaryotic cells Professor Alain Filloux
Subversion of mammalian tyrosine kinases by EPEC and EHEC T3SS effectors Professor Gad Frankel
Structural and functional characterisation of c-di-AMP receptor proteins Professor Angelika Gründling
Survival mechanisms of Staphylococcus aureus under cell wall stress Professor Angelika Gründling
Physiological significance of bacterial heterogeneity during interaction with the host Dr Sophie Helaine
The roles of bacterial virulence mechanisms and host immunity in determining the outcome of infection by invasive African strains of nontyphoidal Salmonella Professor David Holden
The cell biology of zebrafish infection Dr Serge Mostowy
Studying type IV pilus biology in a Gram positive model species Dr Vladimir Pelicic
Melanocortin and TB Dr Brian Robertson
Exploitation of Tenascin-C in Tuberculosis control Dr Brian Robertson
Transcriptional regulation at a major virulence gene expression control operon in Staphylococcus aureus Professor Ramesh Wigneshweraraj
PhD Example Projects