Computational and systems medicine

Our computational and systems medicine researchers work with complex patient data, modelling them in unique and interactive ways that allow clinicians to make better-informed decisions about patient care.

Computational and systems medicine and the iKnife at Imperial College London


In strong collaboration with industry we have established one of the most extensive metabolic research facilities in the world, including 13 state-of-the-art high-field NMR systems and 49 mass spectrometers.

We host the MRC-NIHR National Phenome Centre;  a world class facility for metabolic phenotyping.

In addition, we host two other major laboratories - the Metabolic Spectroscopy Application Laboratory for Biofluid/Tissue Analysis at our South Kensington campus, and the Imperial Clinical Phenotyping Centre and Surgical Metabolomics lab - the first in the world to be integrated into a hospital setting - at St Mary’s Hospital, for patient journey phenotyping. This facility is supported by the Imperial NIHR Biomedical Research Centre (BRC) and builds on our Waters Centre of Innovation status.


Recent research

The iKnife

One of the major research areas within computational and systems medicine is the development of new tools for real time medical diagnostics. The iKnife is one such tool developed in order to get real-time histological data on tissue during disection.

Find out more on the BRC website: An 'intelligent knife' that tells the surgeon where to cut.