Search or filter publications

Filter by type:

Filter by publication type

Filter by year:

to

Results

  • Showing results for:
  • Reset all filters

Search results

  • JOURNAL ARTICLE
    Nicolaou L, Zaki TA, 2016,

    Characterization of aerosol Stokes number in 90 degrees bends and idealized extrathoracic airways

    , JOURNAL OF AEROSOL SCIENCE, Vol: 102, Pages: 105-127, ISSN: 0021-8502
  • JOURNAL ARTICLE
    Nicolaou L, Jung SY, Zaki TA, 2015,

    A robust direct-forcing immersed boundary method with enhanced stability for moving body problems in curvilinear coordinates

    , COMPUTERS & FLUIDS, Vol: 119, Pages: 101-114, ISSN: 0045-7930
  • CONFERENCE PAPER
    Nicolaou L, Zaki TA, 2015,

    On the Stokes number and characterization of aerosol deposition in the respiratory airways

    , 4th International Conference on Computational and Mathematical Biomedical Engineering - CMBE2015, Pages: 224-227, ISSN: 2227-3085

    Aerosol deposition in the respiratory airways has traditionally been examined in terms of the Stokes number based on the reference flow timescale. This choice leads to large scatter in deposition efficiency when plotted against the reference Stokes number because the velocity and length scales experienced by advected particles deviate considerably from the reference values. A time-average of the particle local Stokes number should be adopted instead. Our results demonstrate that this average, or effective, Stokes number can deviate significantly from the reference value, in particular in the intermediate Stokes number range where variation across subjects is largest.

  • CONFERENCE PAPER
    Nicolaou L, Zaki TA, 2015,

    AN IN SILICO LABORATORY FOR PATIENT-SPECIFIC TREATMENT OF ASTHMA AND COPD

    , Publisher: MARY ANN LIEBERT, INC, Pages: A21-A21, ISSN: 1941-2711
  • JOURNAL ARTICLE
    Nicolaou L, Zaki TA, 2013,

    Direct numerical simulations of flow in realistic mouth-throat geometries

    , JOURNAL OF AEROSOL SCIENCE, Vol: 57, Pages: 71-87, ISSN: 0021-8502
  • CONFERENCE PAPER
    Nicolaou L, Zaki TA, 2013,

    An immersed boundary method for patient-specific modelling of flow and aerosol deposition in the extrathoracic airways

    , 3rd International Conference on Computational and Mathematical Biomedical Engineering - CMBE2013, Pages: 414-417, ISSN: 2227-3085
  • CONFERENCE PAPER
    Nicolaou L, Zaki TA, 2012,

    Prediction of flow and aerosol deposition in the extrathoracic airways using an implicit immersed boundary method

    , 9th International ERCOFTAC Symposium on Engineering Turbulence Modeling and Measurements (ETMM9)

    The effect of intrasubject variation on the turbulentflow and aerosol deposition in the extrathoracic airwaysis studied in two realistic mouth-throat geometriesfrom the same subject. An immersed boundarymethod is applied which simplifies the task of gridgeneration for the complex extrathoracic geometriesand allows the use of a structured grid solver. Curvilineargrids that roughly follow the shape of the geometriesare adopted, allowing for much higher resolutionwithin the geometries than Cartesian grids commonlyused in IB methods. An added advantage isthat the grid lines are approximately aligned with thestreamlines, which reduces numerical diffusive errors.The numerical simulations allow us to explain in vitroaerosol deposition data in the literature for the samemouth-throat models. The position of the tongue duringinhalation is shown to have a significant impact onboth the mean flow patterns and the turbulence intensities,which in turn affects extrathoracic deposition.

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-t4-html.jsp Request URI: /respub/WEB-INF/jsp/search-t4-html.jsp Query String: id=760&limit=20&respub-action=search.html Current Millis: 1490821474008 Current Time: Wed Mar 29 22:04:34 BST 2017