Earlier Publications

Earlier Publications

29.  Díez-González, S.; Escudero-Adán, E. C.; Benet-Buchholz, J.; Stevens, E. D.; Slawin, A. M. Z.; Nolan, S. P. ‘[(NHC)CuX] complexes: Synthesis, characterization and catalytic studies’ Dalton Trans. 2010, 39, 7595–7606.

28.  Ramón, R. S.; Bosson, J.; Díez-González, S.; Marion, N.; Nolan, S. P. ‘Au/Ag-cocatalyzed Beckmann rearrangement of aldoximes into primary amides’ J. Org. Chem. 2010, 75, 1197–120 2.

27.  Dí ;ez-González, S.; Marion, N.; Nolan , S . P. ‘N-Heterocyclic carbenes in late-transition metals catalysis’ Chem. Rev. 2009, 1 09, 3612–3676.

26. Broggi, J.; Joubert, N.; Díez-González, S.; Berteina-Raboin, S.; Zevaco, T.; Nolan, S. P.; Agrofoglio, L. A. ‘Synthesis of (±)-1,2,3-Triazolo-4’,4-dihydroxymethyl-carbanuclesides’ Tetrahedron 2009, 65, 1162–1170.

25.  Teysso t, M.-L.; Jarrousse, A.-S.; Chevry, A.; De Haze, A.; Beaudoin, C.; Manin , M.; Nolan, S. P.; Díez-González, S.; Morel, L.; Gautier, A. ‘Toxicity of copper(I)–NHC against human tumor cells: Induction of cell cycle arrest, apoptosis and DNA cleavage’ Chem.-Eur. J. 2009, 15, 314­–318.

24.  Díez-González, S.; Nolan, S. P. ‘[(NHC)2Cu]X complexes as efficient cata lysts for azide-alkyne Click chemistry at low catalyst loadings; Angew. Chem., Int. Ed. 2008, 47, 8881–8884.

23.  Díez-González, S.; Stevens, E. D.; Nolan, S. P. ‘A [(NHC)CuCl] complex as latent Click catalyst’ Chem. Commun.  2008, 4747–4749.

22.  Díez-González, S.; Nolan, S. P. ‘N-Heterocyclic carbene copper complexes: Synthesis and catalysis’ Aldrichimica Acta 2008, 41, 43–51.

21.  Díez-González, S.; Paugam, R.; Blanco, L. ‘Synthesis of 1-silabicyclo[4.4.0]dec-5-en-4-ones: A model of A and B rings of 10-silatestosterone’ Eur. J. Org. Chem. 2008, 3298–3307.

20.  Díez-González, S.; Blanco, L. ‘Synthesis of 2-methylidene-1-silacyclohexanes by intramolecular hydrosilylation’ J. Organomet. Chem. 2008, 693, 2033–2040.

19.  Díez-González, S.; Nolan, S. P. ‘Copper, silver and gold complexes in hydrosilylation reactions’ Acc. Chem. Res. 2008, 41, 349–358.

18.  Broggi, J.; Díez-González, S.; Petersen, J. L.; Berteina-Raboin, S.; Nolan, S. P.; Agrofoglio L. A. ‘Study of copper(I) catalysts for the synthesis of carbanucleosides via azide-alkyne 1,3-dipolar cycloaddition’ Synthesis 2008, 141–148 [Feature article].

17.  Díez-González, S.; Stevens, E. D., Scott, N. M.; Petersen, J. L.; Nolan, S. P. ‘Synthesis and characterization of [Cu(NHC)2]X complexes: Catalytic and mechanistic studies of hydrosilylation reactions’ Chem.−Eur. J. 2008, 14, 158–168.

16.  Díez-González, S.; Nolan, S. P. ‘Transition metal-catalyzed hydrosilylation of carbonyl compounds and imines. A review’ Org. Prep. Proc. Int. 2007, 39, 523–560.

15.  Broggi, J.; Joubert, N.; Aucagne, V.; Berteina-Raboin, S.; Díez-González, S .; Nolan, S.: Topalis, D.; Deville-Bonne, D.; Balzarini, J.; Neyts, J.; Andrei, G.; Snoeck, R.; Agrofoglio, L. A. ‘Alkyne-azide click chemistry mediated carbanucleosides synthesis’ Nucleosides, nucleotides and nucleic acids 2007, 26, 1391–1394.

14.  Díez-González, S.; Nolan, S. P. ‘[(NHC)Copper(I)] complexes in homogeneous catalysis] Synlett 2007, 2158–2167.

13.  Marion, N.; Díez-González S.; Nolan, S. P. ‘N-Heterocyclic carbenes as organocatalysts’ Angew. Chem., Int. Ed. 2007, 46, 2988­–3000.

12.  Lebel, H.; Davi, M.; Díez-González, S.; Nolan, S. P. ‘Copper-carbene complexes as catalysts in the synthesis of functionalized styrenes and aliphatic alkenes’ J. Org. Chem. 2007, 72, 144–149.

11.  Díez-González S.; Nolan, S. P. ‘Stereoelectronic parameters associated with N-heterocyclic carbene (NHC) ligands: A quest for understanding’ Cood. Chem. Rev. 2007, 251, 874–883.

10.  Díez-González, S.; Nolan, S. P. ‘Palladium-catalyzed reactions using NHC ligands’ N-Heterocyclic Carbenes in Transition Metal Catalysis: Top. Organomet. Chem. 2007, 21, 47–82.

9.  Welle, A.; Díez-González, S.; Tinant, B.; Nolan, S. P.; Riant, O. ‘A three-co mponent tandem reductive a ldol reaction catalyzed by N-heterocyclic carbene-copper complexes’ Org. Lett. 2006, 8, 6059–6062.

8.  Díez-González, S.; Correa, A.; Cavallo, L.; Nolan, S. P. ‘(NHC)Copper(I)-catalyzed [3+2] cycloaddition of azides and mono- o r disubstituted alkynes’ Chem.−Eur. J. 2006, 12, 7558–7564.

[Higlighted in Synfacts 2007 (2) 142]

7.  Díez-González, S.; Blanco, L. ‘Synthesis of 2-methylidene-1-silacyclohexanes from 2,6-dibromohex-1-ene and polyhalosilanes’ J. Organomet. Chem. 2006, 691, 5531–5539.

6.  Marion, N.; Díez-González, S.; de Frémont, P.; Noble, A. R.; Nolan, S. P. ‘AuI-Catal yzed tandem [3,3] rearrangement-intramolecular hydroar ylation: Mild and efficient formation of substitute d indenes’ Angew. Chem., Int. Ed. 2006, 45, 3647–3650 [Hot paper].

5.  Díez-González, S.; Scott, N. M.; Nolan, S. P. ‘Cationic copper(I) complexes as e fficient pre-catalysts for the hydrosilylation of carbonyl compounds’ Organometallics 2006, 25, 2355–2358.

4.  Díez-González, S.; Nolan, S. P. ‘Palladium pre-catalysts for cross-coupling reactions’ Spec. Chem. Mag. 2006, Jan/Feb, 26–28.

3.  Díez-González, S.; Nolan, S. P. ‘Carbene and transition metal-mediated transformations’ Ann. Rep. Prog. Chem., Sect. B 2005, 101, 171–191.

2.  Kelly, R. A., III; Scott, N. M.; Díez-González, S.; Stevens, E. D.; Nolan, S. P. ‘Simple synthesis of CpNi(NHC)Cl complexes (Cp = cyclopentadienyl ; NHC = N-heterocyclic carbene)’ Organometallics 2005, 24, 3442–3447.

 1.  Díez-González, S.; Kaur, H.; Zinn, F. K.; Stevens, E. D.; Nolan, S. P. ‘A simple and efficient copper-catalyzed procedure for the hydrosilylation of hindered and functionalized ketones’ J. Org. Chem. 2005, 70, 4784–4796.

Books


RSC Catalysis Series, 2010N-HETEROCYCLIC CARBENES: From Laboratory Curiosities to Efficient Synthetic Tools

Silvia Díez-González, Editor

RSC Catalysis Series, 2010

This book shows how N-heterocyclic carbenes can be useful in various fields of chemistry and not merely laboratory curiosities or simple phosphine mimics. NHCs are best known for their contribution to ruthenium and palladium-catalysed reactions but the scope of this book is much broader. The synthesis of NHC ligands and their corresponding metal complexes are covered in depth. Moreover, the biological activity of NHC-containing complexes, as well as an overview of their theoretical aspects are included. Such metal species are further examined, not only in terms of their catalytic applications, but also of their stereoelectronic parameters and reactivity/stability. Finally, special attention is given to the hot topic of organocatalysis. This book will be of interest to postgraduates, academic researchers and those working in industry.

 

Peer-Reviewed Publications


TOC15. Zelenay, B.; Frutos-Pedreño, R.; Markalain-Barta, J.; Vega-Isa, E.; White, A. J. P.; Díez-González, S.

‘Homo- and heteroleptic copper(I) complexes with diazabutadiene ligands: Synthesis, solution- and solid-state structural studies’

Eur. J. Inorg. Chem. 2016, 4649–4658


toc14. Collinson, J.-M.; Wilton-Ely, J. D. E. T.; Díez-González, S.

‘Functionalised [(NHC)Pd(allyl)Cl] complexes: Synthesis, immobilisation and application in cross-coupling and dehalogenation reactions’

 Catal. Commun. 2016, 87, 78–81


13. Pérez, J. M.; Crosbie, P.; Lal, S.; Díez-González, S.toc

‘Copper(I)‒phosphinite complexes in Click chemistry : Three component reactions and preparation of 5-iodotriazoles’

ChemCatChem 2016, 8, 2222–2226


'HBF4-Catalysed Nucleophilic Substitutions of Propargylic Alcohols'12. Barreiro, E.; Sanz-Vidal, A.; Tan, E.; Lau, S.-H.; Sheppard, T. D.; Díez-González, S.

'HBF4-Catalysed nucleophilic substitutions of propargylic alcohols'

Eur. J. Org. Chem. 2015, 7544-7549

 


'Catalytic and mechanistic studies of N-heterocyclic carbene or phosphine-containing copper(I) complexes for the synthesis of 5-iodo-1,2,3-triazoles'11. Lal, S.; Rzepa, H. S.; Díez-González, S.

'Catalytic and mechanistic studies of N-heterocyclic carbene or phosphine-containing copper(I) complexes for the synthesis of 5-iodo-1,2,3-triazoles'

ACS Catalysis 2014, 4, 2274-2287

 


10. Carmona, D.; Lamata, M. P.; Sánchez, A. Viguri, F.; Rodríguez, R.; Oro, L. A.; Liu, C.; Díez-González, S.; Maseras, F.10. Carmona, D.; Lamata, M. P.; Sánchez, A. Viguri, F.; Rodríguez, R.; Oro, L. A.; Liu, C.; Díez-González, S.; Maseras, F.

'Chiral transition-metal complexes as Brønsted-acid catalysts for the asymmetric Friedel-Crafts hydroalkoxylation of indoles' 

Dalton Trans. 2014, 43, 11260-11268

This article is part of the themed collection 'Synergy between experimental and theory'

'Chiral transition-metal complexes as Brønsted-acid catalysts for the asymmetric Friedel-Crafts hydroalkoxylation of indoles

 


9. Collinson, J.-M.; Wilton-Ely, J. D. E. T.; Díez-González, S. toc

'Reusable and highly active supported copper(I)–NHC catalysts for Click chemistry'

Chem. Commun. 2013, 49, 11358-11360

This article is highligted in the back cover of the issue:

Immobilised [Cu(NHC)] catalysts are reported for the Click preparation of 1,2,3-triazoles; these are highly active, easy to prepare and to recycle.

Immobilised [Cu(NHC)] catalysts are reported for the Click preparation of 1,2,3-triazoles; these are highly active, easy to prepare and to recycle.


Well-defined diimine copper(I) complexes as catalysts in Click azide-alkyne cycloaddition reactions'8. Markalain-Barta, J.; Díez-González, S. 

 ‘Well-defined diimine copper(I) complexes as catalysts in Click azide-alkyne cycloaddition reactions'

Molecules 2013, 18, 8919–8928

[Invited contribution to special issue on 'Advances in Click Chemistry']


7. Martínez-Sarti, L.; Díez-González, S.toc

‘On the unique reactivity of Pd(OAc)2 with organic azides: Expedient synthesis of nitriles and imines’ 

ChemCatChem 2013, 5, 1722–1724

[Online Open article]


6. Gautier, A.; Cisnetti, F.; Díez-González, S.; Gibard C. 

'Synthesis of 1,3-bis(2,4,6-trimethylphenyl)imidazolium salts: SIMes∙HBr, SIMeS∙HBF4 and SIMes∙HPF6

 Protocols Exchange 2012, doi:10.1038/protex.2012.048


'Novel phosphinite and phosphonite copper(I) complexes: Efficient catalysts for Click azide-alkyne cycloaddition reactions'5. Lal, S.; McNally, J.; White, A. J. P.; Díez-González, S.

'Novel phosphinite and phosphonite copper(I) complexes: Efficient catalysts for Click azide-alkyne cycloaddition reactions'

Organometallics 2011, 30, 6225–6232


Well-defined copper(I) complexes for Click azide-alkyne cycloaddition reactions: One Click beyond4. Díez-González, S. 

‘Well-defined copper(I) complexes for Click azide-alkyne cycloaddition reactions: One Click beyond’ 

Catal. Sci. Technol., 2011, 1, 166–178 

[Hot Article; Invited contribution]

This Perspective was featured in the inside front cover.


 'The use of ligands in copper-catalyzed [3+2] azide-alkyne cycloaddition: Clicker than Click chemistry?'3. Díez-González, S.

'The use of ligands in copper-catalyzed [3+2] azide-alkyne cycloaddition: Clicker than Click chemistry?'

Current Org. Chem. 201 1, 15, 2830-2845


‘[CuBr(PPh3)3] for azide alkyne cycloaddition reactions under true Click conditions’2. Lal, S.; Díez-González, S. 

‘[CuBr(PPh3)3] for azide alkyne cycloaddition reactions under true Click conditions’

J. Org. Chem. 2011, 76, 2367–2374


 1. Díez-González, S.

‘N-Heterocyclic carbenes in copper-catalyzed react ions’ Ideas in Chemistry and Molecular Science, Vol. 1; Advances in Synthetic Chemistry, Wiley-VCH, 2010 pp 43–66.