Research TopicInvestigators/Description
 Pulse wave Propagation in Arterial Networks  Jordi Alastruey, Kim Parker, Joaquim Peiro, Spencer Sherwin, Peter Weinberg
Pulse wave propagation in arterial networks is studied using the 1-D equations of blood flow in compliant vessels, which are solved using a discontinuous Galerkin scheme.
 Mixing in Helical Bypass Grafts  Andrew Cookson, Spencer Sherwin, Denis Doorly
To investigate the fluid dynamical properties of helical pipes, particularly from a mixing perspective, in order to quantify and understand their potential for use as artery bypass grafts and arterio-venous shunts
 Fluid-Structure Interaction of Heart Valves

  Raoul van Loon, Joaquim Peiro, Spencer Sherwin
The interaction between deformable solid bodies (e.g. heart valves) and a fluid are studied using ALE and fictitious domain approaches. Models have been developed in 2D and 3D finite element codes.

 Large Angle Branching with Equal Proximal to Distal Flow Split

 Spencer Sherwin

 Reconstruction and Flow in a Stented and Unstented Pig Carotid Artery Bypass  

Peter Franke, Denis Doorly, Spencer Sherwin, Joaquim Peiro, Colin Caro

The long-term success of arterial bypass grafting with autologous saphenous veins is limited by neointimal hyperplasia (NIH). Placement of a loose-fitting, porous stent around end-to-end, or end-to-side, autologous saphenous vein grafts has been found significantly to reduce NIH, but the mechanism is unclear.

 Computational Fluid Models for Anastomoses  

Spencer Sherwin

In this study a series of model anastomoses are considered under varying geometric conditions with symmetric and asymmetric inflow profiles.

 Geometric Characterisation of Peripheral Bypass Grafting  

Principal: Colin Caro, Nick Cheshire, Spencer Sherwin

Clinical: Jeremy Crane

Academic: Denis Doorly, Kyung Eun Lee, Sergio Giordana, Yannis Papaharilaou, Joaquim Peiro

In this study MRI imaging, duplex ultrasound and CFD are used to reconstruct the geometry and flow environment in in-vivo patients. The aim is to gain an indication of the influence of graft geometry and the associated flow on the development of vascular disease.

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